Advanced solution regarding Internal standards for biomarker discovery and reproducibility

The advanced metabolic profiling tools have been helping in eliminating all the relevant hassles in an incomparable way. Therefore, when it comes to simplifying the research process in the realm of internal standards for biomarker discovery and reproducibility, why still depend on conventional metabolic profiling tools?
In this article, you can learn how IROA TruQuant (IQQ) Measurement System can contribute to biomarker discovery and reproducibility.

IROA TruQuant (IQQ) Measurement System — Advancing biomarkers discovery and reproducibility
The clinically relevant biomarker data needs to be reproducible while the clinically relevant metabolomics requires accurate identification, performance criteria for complete reproducible quantitation and instrumentation. And this is possible only with the support of the of advanced metabolic profiling accessories. Considering this, the advanced metabolomics companies are striving to invent advanced metabolomics tools.

IROA Technologies LLC is a trusted metabolomics company introducing IROA TruQuant (IQQ) Measurement System. In the points attached below, you can learn the significance of this tool in the domain of internal standards for biomarker discovery and reproducibility:
• This provides cost-effective and immediate metabolite identification and quantitation.

• All the IROA-based fragments will have the IROA ratio pattern of their relevant parent peaks. And these can be identified as such using the ‘peak correlation’ ClusterFinder module.

• The setting of all peaks in the chromatogram utilizing the IROA-IS generation retention Time ladder.

• The retention index within the sample permits the unidentified elements to be tracked in an accurate process. The spiked-in internal standard that contains 100s of identified compounds offers accurate compound formula ID for MS alone, complete ID along with SWATH or IM. And all these are made possible at lower concentrations.

• The unique IROA patterns differentiate the peaks of biological origin from artefactual peaks. And these contribute to eliminating false data in the internal standards for biomarker discovery and reproducibility.

• The ClusterFinder software solutions help in developing libraries, IDs/quantitate compounds and this also normalizes data.

• This ensures high-level QC for accurate and reproducible data.

• The suppression-correlated measures are generated for enhanced quantitation.

• This normalizes the suppression corrected experimental samples to overcome day-to-day and instrument-to-instrument discrepancies.

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